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New daily weight loss pill could be a game changer! It’s called Orforglipron

Robert Price | Last update: 6th May 2025

Big news on the horizon: a daily weight loss pill called orforglipron has shown promising results in clinical trials. Developed by Lilly (the makers of Mounjaro), this GLP-1 drug helped participants lose around 8% of their body weight over 10 months.

Unlike injections, this is a once-a-day pill designed to reduce appetite and help you feel full quicker. Early trial results suggest it’s just as effective – and just as safe – as existing injectable GLP-1s.

New daily weight loss pill could be a game changer! It’s called Orforglipron

Why It Matters

For many people, the idea of taking a pill instead of injecting is much more appealing. It’s easier to travel with, doesn’t need refrigerating, and can be taken any time of day, with or without food. Handy, right?

Professor Rachel Batterham from Lilly says most of her patients ask for tablets over injections – and this could finally be the answer. Plus, pills mean less plastic waste and fewer supply issues down the line.

What’s Next?

Lilly plans to apply for UK approval by the end of this year. If all goes well, the pill could be available privately in 2025 – and possibly through the NHS not long after.

A Few Things to Note

Side effects are similar to other GLP-1s – nausea, diarrhoea, and occasional vomiting are possible. And as always, these drugs aren’t magic. They work best when combined with changes to diet, exercise and overall lifestyle.

Final Thoughts

A daily weight loss pill could make managing weight more accessible and more flexible for a lot of people – especially those who’ve struggled with injections. We’ll be keeping a close eye on this one.

Would you prefer a daily pill to an injection? Let us know – start a chat👇

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